Meet the WGGC Collaborative Network

The West German Genome Center (WGGC) is a collaborative network of Universities and institutes located across western Germany. We facilitate centralized access to sequencing services while leveraging the distributed expertise in genomics and bioinformatics from our collaborative institutions.

Such collective strength enables WGGC to support most aspects of NGS research, with particular depth in human and medical genetics as well as onco- and plant genomics.

Our four sequencing hubs – facilities at the universities of Aachen, Bonn, Cologne, and Düsseldorf – are equipped with state-of-the-art technologies and offer the entire repertoire of sequencing analysis techniques. Together, they form a robust infrastructure designed to meet demands of high volume and complex research projects.

Together, the WGGC partners form a powerful alliance committed to advancing research through innovation, collaboration, and technical excellence in genomics.

In 2024, the sequencing facility of RWTH Aachen joined our network and has since made significant contributions to our shared NGS competencies, particularly through its strong bioinformatics expertise.

The Cologne Center for Genomics (CCG) has evolved into one of the leading German university-based, high-capacity NGS production sites for a large variety of taxa over the past decade

At the University of Bonn, the NGS core facility together with the German Centre for Neurodegenerative Diseases (DZNE) have a strong track-record in high-throughput genomics for complex disease research and have become a leader in single-cell genomics.

The University of Düsseldorf contributes deep expertise in both short-read and long-read sequencing technologies, advancing precision analysis in diverse research domains.

The WGGC Timeline

DFG Application | West German Genome Center founded
“...The WGGC will bundle capacity and expertise to all scientists with the next generation sequencing demands in Western Germany and assist them in conducting nationally and internationally competitive research…”

- DFG Project Description
DFG Application | Next Generation Sequencing Competence Network founded
WGGC, together with the genomic facilities in Kiel, Dresden, and Tübingen Universities and University Hospitals, prepared and submitted a successful application to establish the nationwide Next Generation Sequencing Competence Network (NGS-CN). The DFG began announcing centralized annual Calls for complex sequencing projects.
DFG Call 1
WGGC launched operations with the first DFG funding call for the NGS-CN consisting of more than 50 sequencing projects, initiating service development and infrastructure setup.
DFG Call 2
The second DFG call supported NGS-CN’s continued expansion of genomic services and collaborative research capacity taking in more than 40 sequencing projects which were distributed across partner locations.
DFG Call 3
WGGC strengthened its research network and service portfolio through participation in the third NGS-CN DFG funding call consisting of more than 50 sequencing projects
DFG Call 4
WGGC participated in the fourth DFG call for the NGS-CN consisting of more than 50 sequencing projects, building on its experience in managing large-scale sequencing projects. Funding Extension WGGC secured a funding extension, ensuring continued service delivery and long-term sustainability.
DFG Call 5
The fifth DFG call for the NGS-CN consisting of about 40 sequencing projects enabled WGGC to further broaden its user base and deepen scientific partnerships.
Funded by MKW.NRW
With funding from the Ministry of Culture and Science of the German state of North Rhine-Westphalia (MKW.NRW), WGGC continues to deliver cutting-edge genomic services to the scientific community while also providing robust educational opportunities for early-career researchers and professionals. Open DFG Call for sequencing projects The DFG now offers additional opportunities to apply for funding for projects with high sequencing costs in collaboration with academic sequencing institutions. Furthermore, projects with sequencing costs in both medical and non-medical settings can be funded.
Joint Scientific Establishment founded

The West German Genome Center has been placed on a new legal foundation as a Joint Scientific Establishment, enabling expansion of genome research in medicine and life sciences at an international level.

The center continues to provide cutting-edge genome technologies for medical research, biodiversity studies, plant breeding, and other areas of genetics.

2017 / 2018
2017 / 2018
2019
2020
2021
2022
2023
2024 - present
2025 - present

Our mission

NGS is the sole technology that belongs to the area of life sciences among the top ten most influential technologies for the next 2 decades. Making the WGGC internationally competitive is a clearly formulated goal. We support the concept of concentration and harmonization of NGS infrastructures at the federal level. 

As part of the university network of North Rhine-Westphalia, WGGC not only delivers sequencing services but also fulfills an educational mission. We support the consolidation and harmonization of NGS infrastructure at the national level and contribute to training the next generation of scientists through workshops, teaching, and strong engagement in regional academic programs.

For the first time, our network structure brings together a broad foundation of genomic expertise from institutions where NGS has become a strategic pillar of university development. The WGGC offers an outstanding platform for advancing collaborative research – both within the network and through external partnerships – further driving innovation in genome-based science.

Genomics Facility IZKF

Aachen

The Genomics Facility of the Interdisciplinary Centre for Clinical Research (IZKF) in Aachen supports sequencing projects for the WGGC, offering both long- and short-read sequencing solutions. They utilize Illumina platforms and Oxford Nanopore technologies while aiming to increase the single-cell sequencing portfolio. With extensive expertise in bioinformatics, they provide comprehensive support for data analysis and interpretation.

Key Technology
Special Research
Genomics & Transcriptomics Laboratory (GTL)

Düsseldorf

The Genomics & Transcriptomics Laboratory (GTL) is the WGGC’s dedicated site for long-read sequencing and high-throughput projects. It offers DNA/RNA QC, Sanger and fragment analysis, as well as NGS via PacBio and Oxford Nanopore platforms. The GTL also supports single-cell and spatial transcriptomics (10X Genomics, BD, Parse) and provides expert assistance with both primary and secondary data analysis.
Key Technology
Special Research
Cologne Center for Genomics (CCG)

Köln

The Cologne Center for Genomics (CCG) is the largest WGGC site and offers a broad range of NGS services, including short- and long-read sequencing, methyl-seq, exome, and single-cell protocols. CCG supports customized workflows and leverages the HPC cluster RAMSES via the University of Cologne’s IT Center. This ensures efficient and secure data analysis tailored to the demands of high-throughput life science research.
Key Technology
Special Research
NGS Core Facility

Bonn

The Next Generation Sequencing (NGS) Core Facility at the Institute of Human Genetics at the Medical Faculty of the University Bonn, is a leading platform for state-of-the-art OMICS analyses. The core facility offers a comprehensive range of advanced sequencing technologies including short- and long-read platforms and analytical solutions for genomic, transcriptomic, epigenetic and proteomic research. The NGS Core facility provides researchers with expert support for NGS projects from project planning through the generation of high-quality data and bioinformatic support for downstream data analysis and interpretation.
Key Technology
Special Research

PRECISE

The “Platform foR SinglE Cell GenomIcS and Epigenomics” PRECISE is a joint venture between the University of Bonn and the German Center for Neurodegenerative Diseases (DZNE) in Bonn. PRECISE is dedicated to advancing single-cell multi-omics research through cutting-edge tools and technologies. Our mission is to develop, integrate, and rigorously test innovative methods that are faster, more affordable and highly sensitive.

This commitment allows us to provide, next to highly standardized workflows for bulk RNA-Seq, advanced solutions for single-cell RNA sequencing, including the groundbreaking Flash-Seq approach, high-throughput systems such as BD Rhapsody and 10X Genomics or single cell long reads RNA-Seq. Over the last year, PRECISE has also established a new area of competence in the field of spatial transcriptomics implementing state-of-the-art solutions like Slide-Seq or the Xenium In Situ platform from 10X.

Key Technology
Special Research